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Yes. Go to Options>Advanced>Preferences (or press F12) and, in the “Weight Function, m = ” field write n*((1-y)*m+y*(1-m))/(m*(1-m))^2. This will give you the minimum χ2 estimate of the regression parameters (See example).

Remark: this example illustrates the possibilities offered by CombiStats. The default method – which is also the method of choice in the European Pharmacopoeia – is estimation by Maximum Likelihood.

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