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Answer:

ICRS are supplied in adequate quantities for immediate use after opening the vial. Provided an unopened vial is stored under the recommended conditions, the ICRS will remain suitable for its intended purpose for as long as the batch remains valid. Once a vial has been opened, it is the responsibility of the user to evaluate and ensure its continued suitability.

Storage conditions are given in the list of ICRS available on the EDQM website and only apply to unopened vials.

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