The definition of substance X gives the content on dried or anhydrous basis. What about the solvents, are they to be taken into account when determining the assay?

The definition of substance X gives the content on dried or anhydrous basis. What about the solvents, are they to be taken into account when determining the assay?

In accordance with the general monograph Substances for pharmaceutical use (2034), the content of residual solvents is taken into account for calculation of the assay content of the substance, the specific optical rotation and the specific absorbance. This information is therefore not indicated in the specific monographs concerned.