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Answer:

It is the policy of WHO not to ASSIGN an expiry date to their international reference standards. They remain valid with the assigned potency and status until withdrawn or amended. Reference standards are held at the EDQM within assured, temperature-controlled storage facilities. Storage instructions are shown on the label of the standards. Where available stability information about a particular standard is detailed on the leaflet supplied with the standard. 

Users who have data supporting any deterioration in the characteristics of any reference standard are encouraged to contact the EDQM.

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