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‘Unless otherwise stated, in a test or assay, the symmetry factor (tailing factor) of the peak used for quantitation is 0.8-1.8.’

When developing a monograph, the rapporteurs may notice that the default peak symmetry requirement (0.8-1.8) is not applicable, necessitating the provision of a specific requirement in the monograph. This approach has been followed by Ph. Eur. expert groups for decades and more than 100 monographs include a different minimum or maximum peak symmetry requirement.