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‘The signal-to-noise ratio is used to define the system sensitivity. The limit of quantitation (corresponding to a signal-to-noise ratio of 10) is equal to or less than the reporting threshold.’

This requirement concerns all LC or GC analytical procedures stated in the TESTS section of a monograph and which include a reporting threshold (or disregard limit in older monographs); it does not concern those included under the ASSAY section.

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