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  • Monocyte-activation test (MAT) (general chapter 2.6.30) for broad pyrogen detection;
  • Bacterial endotoxins test (BET) using:
    • limulus amoebocyte lysate (LAL)-based methods (general chapter 6.14);
    • recombinant factor C (rFC) (previously general chapter 6.32, in general chapter 2.6.14. as of Issue 13.1).

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